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An innovative collaboration between NIIMBL, BioPhorum and industry partners to develop a prototype for a Buffer Stock Blending (BSB) Skid is the focus of Kevin Gibson's presentation at ISPE's Young Professionals Pharma 4.0 afternoon event on Wednesday 18th November.
“Buffers are critical inputs into all downstream bioprocessing steps for the manufacture of therapeutic proteins and other biomolecules," said Kevin "The large volumes of buffer required present ongoing logistical challenges and represent a significant portion of facility footprint, labour requirements and equipment costs".
The collaboration between NIIMBL, BioPhorum and various industrial partners has designed and built a prototype for a Buffer Stock Blending (BSB) Skid which will facilitate the preparation of buffers inline, on demand from concentrated single component stock solutions.
Kevin is a Process Engineer at PM Group. He will present as part of an ISPE Ireland Affiliate Young Professionals virtual seminar focusing on Bio Process Controls in the Life Sciences Industry. Kevin will provide an overview of the Buffer Stock Blending system. This will be capable of supplying, in an automated manner, all buffers required for typical purification processes at a quality that is acceptable and equivalent to traditional batch buffer preparation. He will also give an insight into the economic benefits of the technology adoption for both intermediate and large scale manufacturing facilities.
This afternoon virtual seminar on Wednesday 18th November.