Innovative modular vaccines and biologics facilities
Modular production facilities in France and Singapore are a ‘World First’.
About Modulus
Sanofi’s Modulus facilities represent a paradigm shift in vaccine and biologics manufacturing. They are first-of-their-kind modular, scalable, AI-enabled facilities designed to produce multiple vaccine platforms and biologics simultaneously.
Modulus has been recognised with several International awards. The lastest is Overall Winner of ISPE's Facility of the Year Awards.
The Modulus facilities design was unique in that it was replicated across two international locations; a greenfield campus in Tuas, Singapore, and a major expansion on the established Sanofi campus in Neuville-sur-Saône, France.
Recognition:
ISPE FOYA
Overall Winner 2026
Recognition:
ISPE FOYA
'Innovation - Facility of the Future' Category Winner, 2026
Recognition:
TIME
TIME Magazine, Best inventions of 2025, Medical & Healthcare category
“PM Group were A&E designers of the Modulus facilities from Concept through to Detailed Design. Their design was a result of true partnership and innovation collaboration with our clients, and the commitment of our team."
Austin Lock
Head of Technology
Innovative features
Modulus redefines agility, scalability, and sustainability in vaccine production.
The facilities modular design enables rapid reconfiguration for multiple products and process backbones - including mRNA, viral vectors, recombinant proteins, enzymes, and monoclonal antibodies.
Their operational agility is matched by strategic flexibility. The facilities are designed to accommodate multiple ‘product changes’ over time, with adaptable production bay sizes. This allows Sanofi to repurpose and extend the asset without major reconstruction. The approach maximizes utilization and minimizes environmental impact.
Related specialist
Modular approach
The heart of the Modulus facilities innovation is its plug-and-produce modular architecture.
Each production area is equipped with standardized docking stations - utility and service hubs designed to accommodate a wide variety of unit operations and equipment. The approach allows manufacturing lines to be rapidly reconfigured for different products or processes.
The production ballroom can also be adapted for different biosafety requirements. This facilitates switching between products with varying containment needs. Modulus' design enables changeovers in a matter of days. This flexibility supports concurrent multi-product manufacturing. It also allows Sanofi to quickly respond to shifts in market demand or public health needs, such as during a pandemic.
Advanced automation
Modulus features a highly automated end-to-end material handling system, including autonomous mobile robots (AMRs), standardized kitting crates and totes, and semi-automatic kitting operations. Materials are transferred through air showers, undergo robotic ultraviolet light decontamination, and are delivered to production areas via the appropriate combination of conveyors and AMRs, minimizing manual handling and contamination risk.
Digitally enabled
The Modulus sites are underpinned by a fully digitalized architecture. Their digital twin environment enables real-time monitoring, predictive maintenance, and seamless integration of information technology and operational technology systems. The convergence of manufacturing execution systems, distributed control systems, library information management systems, and robotics platforms ensures data integrity, operational transparency, and rapid troubleshooting.
Designed and developed to meet the health challenges of patients around the world, Modulus is setting new standards for agility, digitalization, sustainability, and global replicability.
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